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Beilstein J. Org. Chem. 2023, 19, 107–114, doi:10.3762/bjoc.19.11
Graphical Abstract
Scheme 1: Synthesis of ether triazolopyrazine derivatives 4–9.
Scheme 2: Synthesis of fluorinated triazolopyrazine compounds (10–18) via Diversinate™ chemistry.
Figure 1: Key HMBC, COSY and ROESY correlations, and ORTEP drawing of 18.